With osteoarthritis
7,5 mg per day. If necessary, this dose can be increased to 15 mg per day.
With rheumatoid arthritis
15 mg per day. Depending on the therapeutic effect, this dose can be reduced to 7.5 mg per day.
With ankylosing spondylitis
15 mg per day. Depending on the therapeutic effect, this dose can be reduced to 7.5 mg per day. In patients with an increased risk of adverse reactions, it is recommended to start treatment with a dose of 7.5 mg per day. дозы 7,5 мг в сут.
In patients with severe renal failure on hemodialysis
the dose should not exceed 7,5 mg per day.
Teens
the maximum dose in adolescents is 0,25 mg / kg. The drug should be used in adolescents over 12 years лет