NSAID
- Active ingredient (INN)
- dexketoprofen
- Composition (active ingredients)
- dexketoprofen trometamol - 39,6 mg, in terms of dexketoprofen - 25,0 mg
- Фармакотерапевтическая группа
- non-steroidal anti-inflammatory drug (NSAID)
- Pharmacotherapeutic group
- solution for intravenous and intramuscular administration of 25 mg / ml 2 ml № 3, 5
- Сonditions of supply
- on prescription
Indications
The drug is intended for symptomatic therapy, reduce pain and inflammation at the time of use, does not affect the progression of the disease.- relief of pain syndrome of various origins (including postoperative pain, pain with bone metastases, post-traumatic pain, pain with renal colic, algodismenorea, sciatica, radiculitis, neuralgia, toothache);
- symptomatic treatment of acute and chronic inflammatory, inflammatory-degenerative and metabolic diseases of the musculoskeletal system (including rheumatoid arthritis, osteoarthritis, spondylitis: ankylosing spondylitis, reactive arthritis, psoriatic arthritis).
Dosage regimen
Intravenously (slowly for at least 15 seconds) and intramuscularly (administered deeply, slowly).
- Adults
-
50 mg every 8-12 hours. If necessary, re-administration of the drug with a 6-hour interval is possible. The maximum daily dose of 150 mg. Dexketoprofen is indicated for short-term use (no more than 2 days) during the period of acute pain
- Impaired liver function
-
in patients with mild to moderate hepatic impairment (5-9 points on the Child-Pugh scale), the total daily dose should be reduced to 50 mg and frequent monitoring of liver functional parameters should be carried out. Dexketoprofen should not be prescribed to patients with severe hepatic impairment
- Impaired renal function
-
for patients with mild renal impairment (creatinine clearance - 30-60 ml / min), the daily dose is reduced to 50 mg. Dexketoprofen should not be prescribed to patients with moderate or severe renal failure (creatinine clearance less than 30 ml / min)
- Elderly patients
-
dose adjustment for elderly patients is usually not required, however, due to the physiological decrease in renal function, it is recommended to reduce the dose of the drug: a total daily dose of 50 mg for mild renal impairment in elderly patients
