Anti-bacterial
- Active ingredient (INN)
- azithromycin
- Composition (active ingredients)
- azithromycin dihydrate - 131,027 mg (in terms of azithromycin - 125,0 mg), 524,109 mg (in terms of azithromycin - 500,0 mg)
- Фармакотерапевтическая группа
- antibiotic azalide
- Pharmacotherapeutic group
- film-coated tablets 125 mg №6, 500 mg №3
- Сonditions of supply
- on prescription
Indications
Infectious and inflammatory diseases caused by microorganisms sensitive to azithromycin:- infections of the upper respiratory tract and ENT organs (pharyngitis/tonsillitis, sinusitis, otitis media);
- lower respiratory tract infections (acute bronchitis, exacerbation of chronic bronchitis, pneumonia, including those caused by atypical pathogens);
- infections of the skin and soft tissues (acne vulgaris of moderate severity, erysipelas, impetigo, secondarily infected dermatoses);
- urinary tract infections caused by Chlamydia trachomatis (urethritis, cervicitis);
- the initial stage of Lyme disease (borreliosis) - erythema migrans (erythema migrans)
Dosage regimen
Inside, without chewing, 1 hour before or 2 hours after eating, 1 time per day.
- Adults and children over 12 years of age weighing over 45 kg
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- For infections of the upper and lower respiratory tract, ENT organs, skin and soft tissues
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500 mg once a day for 1 dose for 3 days (course dose - 1,5 g)
- For moderate acne vulgaris
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500 mg once a day for 3 days, then 500 mg once a week for 9 weeks (course dose 6,0 g). The first weekly dose of 500 mg should be taken 7 days after taking the first daily dose of 500 mg (8th day from the start of treatment), the next 8 weekly doses of 500 mg - with an interval of 7 days
- For urinary tract infections caused by Chlamydia trachomatis (urethritis, cervicitis)
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once 1 g
- With Lyme disease (the initial stage of borreliosis) - erythema migrans (erythema migrans)
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1 g on the first day and 500 mg daily from 2 to 5 days (course dose - 3 g)
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- Children from 3 to 12 years old with a body weight of up to 45 kg
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- For infections of the upper and lower respiratory tract, ENT organs, skin and soft tissues
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at the rate of 10 mg/kg body weight 1 time per day for 3 days
- For streptococcus pyogenes pharyngitis/tonsillitis
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20 mg/kg once a day for 3 days (course dose 60 mg/kg). The maximum daily dose is 500 mg
- When treating the initial stage of Lyme disease (erythema migrans)
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20 mg/kg once a day on the first day, then at the rate of 10 mg/kg once a day from 2 to 5 days (course dose 60 mg/kg)
In case of impaired renal function in patients with a GFR of 10-80 ml/min, dose adjustment is not required.
In case of impaired liver function: when used in patients with impaired liver function of mild to moderate severity, dose adjustment is not required.
Elderly patients: No dose adjustment required. Since the elderly may already have ongoing proarrhythmogenic conditions, care should be taken when using the drug due to the high risk of developing cardiac arrhythmias, including arrhythmias of the "pirouette" type.
