Diuretics
- Active ingredient (INN)
- spironolactone
- Composition (active ingredients)
- spironolactone - 25,0 mg
- Фармакотерапевтическая группа
- diuretic potassium-sparing agent
- Pharmacotherapeutic group
- 25 mg tablets № 20
- Сonditions of supply
- on prescription
Indications
- essential hypertension (as part of combination therapy);
- edema syndrome in chronic heart failure;
- hypokalemia / hypomagnesemia (as an aid to its prevention during treatment with diuretics and when it is impossible to use other methods of correction of potassium content)
- to establish a diagnosis of primary hyperaldosteronism;
- severe chronic heart failure with standard therapy.
Dosage regimen
Inside. At the same time as eating.
- With essential hypertension
-
the daily dose for adults is 50-100 mg once and can be increased to 200 mg, while the dose should be increased gradually, once every 2 weeks
- With edema syndrome in the presence of chronic heart failure
-
the drug is prescribed daily, for 5 days, 100-200 mg / day in 2-3 doses, in combination with a “loop” or thiazide diuretic, depending on the effect, the daily dose is reduced to 25 mg, the maintenance dose is selected individually
- With hypokalemia and / or hypomagnesemia caused by diuretic therapy
-
prescribe the drug at a dose of 25-100 mg / day, once or in several doses, the maximum daily dose is 400 mg, if potassium preparations for oral administration or other methods of replenishing its deficiency are ineffective
- In the diagnosis and treatment of primary hyperaldosteronism
-
the drug is prescribed for 4 days at 400 mg / day, distributing the daily dose in several doses per day
- With edema in children from 3 years
-
the initial dose is 1-3,3 mg/kg body weight or 30-90 mg / m² / day. in 1-4 doses, after 5 days the dose is adjusted and, if necessary, increased by 3 times compared to the initial
In elderly patients, it is recommended to start treatment with a minimum dose and titrate it until the maximum dose is achieved under the control of liver and kidney function.
