Diuretics

Rx

VED

Spironolactone Velpharm  

Spironolactone Velpharm

Rx

VED

Active ingredient (INN)
spironolactone
Composition (active ingredients)
spironolactone - 25,0 mg
Фармакотерапевтическая группа
diuretic potassium-sparing agent
Pharmacotherapeutic group
25 mg tablets № 20
Сonditions of supply
on prescription
Indications

Indications

  • essential hypertension (as part of combination therapy);
  • edema syndrome in chronic heart failure;
  • hypokalemia / hypomagnesemia (as an aid to its prevention during treatment with diuretics and when it is impossible to use other methods of correction of potassium content)
  • to establish a diagnosis of primary hyperaldosteronism;
  • severe chronic heart failure with standard therapy.
Dosage regimen

Dosage regimen

Inside. At the same time as eating.

With essential hypertension

the daily dose for adults is 50-100 mg once and can be increased to 200 mg, while the dose should be increased gradually, once every 2 weeks

With edema syndrome in the presence of chronic heart failure

the drug is prescribed daily, for 5 days, 100-200 mg / day in 2-3 doses, in combination with a “loop” or thiazide diuretic, depending on the effect, the daily dose is reduced to 25 mg, the maintenance dose is selected individually

With hypokalemia and / or hypomagnesemia caused by diuretic therapy

prescribe the drug at a dose of 25-100 mg / day, once or in several doses, the maximum daily dose is 400 mg, if potassium preparations for oral administration or other methods of replenishing its deficiency are ineffective

In the diagnosis and treatment of primary hyperaldosteronism

the drug is prescribed for 4 days at 400 mg / day, distributing the daily dose in several doses per day

With edema in children from 3 years

the initial dose is 1-3,3 mg/kg body weight or 30-90 mg / m² / day. in 1-4 doses, after 5 days the dose is adjusted and, if necessary, increased by 3 times compared to the initial

In elderly patients, it is recommended to start treatment with a minimum dose and titrate it until the maximum dose is achieved under the control of liver and kidney function.

Contraindications

There are contraindications, consult with a specialist before use