Dosage regimen
Orally (during or after meals, drinking plenty of water at each dose).
- With a headache
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1-2 tablets, in case of severe headache, the next dose is possible after 4-6 hours. For the treatment of headaches and migraines, the drug is used for no more than 4 days
- With migraine
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2 tablets at the onset of symptoms, if necessary, repeated administration after 4-6 hours.To treat headaches and migraines, the drug is used for no more than 4 days
- With pain syndrome
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1-2 tablets; average daily dose - 3-4 tablets, maximum daily dose - 8 tablets. The drug should not be taken for more than 5 days as an analgesic and for more than 3 days as an antipyretic
Seniors (over 65).
Care should be taken in elderly patients, especially those with low body weight.
Patients with hepatic and renal impairment.
The effect of impaired liver or kidney function on the pharmacokinetics of the drug has not been studied. Given the mechanism of action of acetylsalicylic acid and paracetamol, their use can aggravate renal or hepatic failure. In this regard, the drug is contraindicated in patients with severe hepatic or renal insufficiency, and with mild to moderate hepatic and renal insufficiency, it should be used with caution.