Antiemetic
- Active ingredient (INN)
- metoclopramide
- Composition (active ingredients)
- metoclopramide hydrochloride monohydrate (in terms of metoclopramide hydrochloride) - 5,0 mg
- Фармакотерапевтическая группа
- gastrointestinal motility stimulator, antiemetic
- Pharmacotherapeutic group
- solution for intramuscular and intravenous administration of 5 mg/ml 2 ml № 10
- Сonditions of supply
- on prescription
Indications
- prevention of postoperative nausea and vomiting;
- symptomatic treatment of nausea and vomiting, including with acute migraine;
- prevention of nausea and vomiting caused by radiation therapy and chemotherapy;
- to enhance peristalsis during X-ray contrast studies of the gastrointestinal tract.
Children:
- second line of treatment for postoperative nausea and vomiting;
- second line for the prevention of delayed nausea and vomiting caused by chemotherapy.
Dosage regimen
Intravenously or intramuscularly.
Intravenous injections should be administered bolus slowly (at least 3 minutes).
Adults:
- prevention of postoperative nausea and vomiting: recommended single dose of 10 mg (1 ampoule);
- the second line of treatment for postoperative nausea and vomiting and the second line of prevention of delayed nausea and vomiting caused by chemotherapy: the recommended single dose of 10 mg (1 ampoule) up to three times a day;
- to enhance peristalsis during X-ray contrast studies of the gastrointestinal tract and as a means of facilitating duodenal sounding: intravenous bolus slow (at least 3 minutes) administration of 10-20 mg (1-2 ampoules) 10 minutes before the start of the study is recommended.
The maximum recommended daily dose is 30 mg or 0,5 mg/kg.
Children from 1 year to 18 years old
- the second line of treatment for postoperative nausea and vomiting and the second line of prevention of delayed nausea and vomiting caused by chemotherapy: intravenous bolus slow (at least 3 minutes) is recommended
0,1-0,15 mg/kg up to 3 times a day.
Dosage regimen:
At the age of 1-3 years with a body weight of 10-14 kg 1 mg up to 3 times a day
At the age of 3-5 years with a body weight of 15-19 kg 2 mg up to 3 times a day
At the age of 5-9 years with a body weight of 20-29 kg 2,5 mg up to 3 times a day
At the age of 9-18 years with a body weight of 30-60 kg 5 mg up to 3 times a day
At the age of 15-18 years with a body weight of more than 60 kg 10 mg up to 3 times a day
The maximum daily dose of 0,5 mg/kg/day.
- to enhance peristalsis during X-ray contrast studies of the gastrointestinal tract and as a means of facilitating duodenal sounding:
а) у children over 15 years of age - recommended intravenous bolus slow (at least 3 minutes), the introduction of 10-20 mg (1-2 ampoules) 10 minutes before the start of the study.
b) in children aged 1 to 15 years, an intravenous bolus slow (at least 3 minutes) is recommended at the rate of 0,1 mg/kg 10 minutes before the start of the study.
The maximum duration of treatment for the prevention of postoperative nausea and vomiting is 48 hours.
The maximum treatment period for the prevention of nausea and vomiting caused by chemotherapy is 5 days.
In order to avoid overdose, it is necessary to observe the minimum interval between the use of 6 hours, even in case of vomiting.